ALG3 as a PanCancer Oncogene: Bioinformatics Analysis and Identification ofSmall-Molecule Inhibitors

The study first reported potential inhibitors of human ALG3 based on a molecular modelling approach. This opens the way for future experimental investigations of the testing of these lead compounds in ALG3-high cancer models.

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Publication Details

Journal
Anti-Cancer Agents in Medicinal Chemistry
Published
2025-11-03
DOI
https://doi.org/10.2174/0118715206395527250902101008
Primary Topic
Glycosylation and Glycoproteins Research
Type
article
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article

ALG3 as a PanCancer Oncogene: Bioinformatics Analysis and Identification ofSmall-Molecule Inhibitors

Sameh S. Elhady, Waleed K. Abdulsahib, Hanadi A. Katouah, Eman Elsayed Fayad et al.
Anti-Cancer Agents in Medicinal Chemistry
Glycosylation and Glycoproteins Research
article

ALG3 as a PanCancer Oncogene: Bioinformatics Analysis and Identification ofSmall-Molecule Inhibitors

Sameh S. Elhady, Waleed K. Abdulsahib, Hanadi A. Katouah, Eman Elsayed Fayad, Khaled M. Darwish, Dalal Sulaiman Alshaya, Mohammed Alshehri, Muhammad Alaa Eldeen, Mohamed O. Andarawi, Hassan M. Otifi, Aiysha Althobaiti, Hesham M. Hassan
article en

Abstract

The study first reported potential inhibitors of human ALG3 based on a molecular modelling approach. This opens the way for future experimental investigations of the testing of these lead compounds in ALG3-high cancer models.

Anti-Cancer Agents in Medicinal ChemistryVol. 26
Princess Nourah bint Abdulrahman University (SA), Suez Canal University (EG), Taif University (SA), King Abdulaziz University (SA), Zagazig University (EG), Umm al-Qura University (SA), King Saud Medical City (SA), King Saud University (SA), Iraqi University (IQ), Andalas University (ID), King Khalid University (SA)
Openalex Percentile: Top 71%
Glycosylation and Glycoproteins Research
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ALG3 as a PanCancer Oncogene: Bioinformatics Analysis and Identification ofSmall-Molecule Inhibitors — Sameh S. Elhady, Waleed K. Abdulsahib, et al. · Anti-Cancer Agents in Medicinal Chemistry (2025) | TGRS Research Map | TGRS