Doxorubicin-Induced Cardiotoxicity: Exploration of Molecular Pathogenesis and Phytocompound-Based Therapeutic Strategies

Plant-derived bioactive compounds show potential in mitigating doxorubicin-induced cardiotoxicity, as supported by preclinical evidence. However, further translational studies are warranted to validate these findings, optimize pharmacokinetics, and evaluate their feasibility in clinical oncology settings.

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Publication Details

Journal
Current Pharmaceutical Design
Published
2025-11-03
DOI
https://doi.org/10.2174/0113816128410093251006160508
Citations
2
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
Field-Weighted Citation Impact
2.78
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article

Doxorubicin-Induced Cardiotoxicity: Exploration of Molecular Pathogenesis and Phytocompound-Based Therapeutic Strategies

Sameer N. Goyal, Harshal D. Pawar, Kartik T. Nakhate, Tarun Sharma et al.
2 citations
Current Pharmaceutical Design
Chemotherapy-induced cardiotoxicity and mitigation
2.78
article

Doxorubicin-Induced Cardiotoxicity: Exploration of Molecular Pathogenesis and Phytocompound-Based Therapeutic Strategies

Sameer N. Goyal, Harshal D. Pawar, Kartik T. Nakhate, Tarun Sharma, Sanskruti Dusane
article en
2 citations

Abstract

Plant-derived bioactive compounds show potential in mitigating doxorubicin-induced cardiotoxicity, as supported by preclinical evidence. However, further translational studies are warranted to validate these findings, optimize pharmacokinetics, and evaluate their feasibility in clinical oncology settings.

Current Pharmaceutical DesignVol. 32
Shri Vile Parle Kelavani Mandal (IN)
Openalex Percentile: Top 8%
Chemotherapy-induced cardiotoxicity and mitigation
2.78
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