Bioinformatics-based Mechanisms of Lipid Metabolism and Endoplasmic Reticulum Stress in Coronary Artery Disease
This study elucidates the pathogenic mechanisms of L-ER RGs in CAD development, identifying NFKB1, LPIN1, and SEC24B as key molecular mediators. It not only reveals their roles in immune regulation and metabolic pathways but also provides actionable targets for precision therapeutics in CAD management.
Authors
- Huaiyu Ruan
- Lili Ye
- Qinyun Chen
- Ruiyan Wang (ORCID: https://orcid.org/0000-0001-5560-6841)
- Mengyu He (ORCID: https://orcid.org/0000-0002-0997-8414)
- Yiming Chen (ORCID: https://orcid.org/0000-0002-8894-2902)
- Ke Wang (ORCID: https://orcid.org/0009-0004-9852-3842)
- Feng Wang (ORCID: https://orcid.org/0000-0003-1089-3095)
- Yuli Huang (ORCID: https://orcid.org/0000-0002-4472-6589)
- Jing Zhou (ORCID: https://orcid.org/0000-0002-5133-740X)
- Jian Song (ORCID: https://orcid.org/0000-0002-2459-7046)
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Endocrine Metabolic & Immune Disorders - Drug Targets
- Published
- 2025-11-03
- DOI
- https://doi.org/10.2174/0118715303432896251016035431
- Citations
- 1
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80