Refining the <i>Sox10</i> <sup>Dom/+</sup> mouse model: A new breeding strategy with relevance to Hirschsprung disease genetics
The breeding strategy of the B6C3Fe-g strain ensures genetic and phenotypic stability, while improving reproductive efficiency, and is an ideal scheme for breeding Sox10<sup>Dom/+</sup> mice.
Authors
- Suyun Huang (ORCID: https://orcid.org/0000-0001-7682-2631)
- Qiuming He
- Chaoting Lan (ORCID: https://orcid.org/0000-0002-6363-9587)
- Jixiao Zeng (ORCID: https://orcid.org/0000-0003-4854-4966)
- Ning Tang (ORCID: https://orcid.org/0000-0003-4702-9399)
- Qiuhua Wang (ORCID: https://orcid.org/0000-0002-0273-3510)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-9556-0240)
- Yu Ouyang (ORCID: https://orcid.org/0000-0001-6473-9283)
- Wei Zhong (ORCID: https://orcid.org/0000-0002-0637-3743)
- Yuxin Wu (ORCID: https://orcid.org/0009-0009-0032-0358)
- Lihua Huang (ORCID: https://orcid.org/0000-0003-0768-2369)
- Xin Zhong (ORCID: https://orcid.org/0000-0003-3281-5709)
- Jiazhang Chen
- Xinying Zhao
- Yide Mu
- Jieting Lu
Institutions
- Liuzhou Maternal and Child Health Hospital (CN)
- Guangzhou Women and Children Medical Center (CN)
- Guangdong Province Women and Children Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Animal Models and Experimental Medicine
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/ame2.70091
- Primary Topic
- Congenital gastrointestinal and neural anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Guangdong Medical Research Foundation
- Basic and Applied Basic Research Foundation of Guangdong Province