Establishment of a neonatal rat model of sequential hyperoxic hypoxia to recapitulate clinical progression of bronchopulmonary dysplasia-associated pulmonary hypertension
The sequential hyperoxic hypoxia model dynamically mimicked the clinical progression of BPD-PH, which may provide a powerful platform for stage-specific mechanism research and development of novel therapeutic strategies.
Authors
- Zhichun Feng (ORCID: https://orcid.org/0000-0001-5964-8379)
- Changgen Liu
- Shanghong Tang
- Jingke Cao
- Siqi Hu (ORCID: https://orcid.org/0000-0002-8354-2950)
- Fan Yang (ORCID: https://orcid.org/0000-0001-7736-1873)
- Ye Ma (ORCID: https://orcid.org/0000-0001-5262-1130)
- Yunbin Xiao
- Haoqin Fan
- Qiuping Li (ORCID: https://orcid.org/0000-0001-9363-7577)
- Dan Wang (ORCID: https://orcid.org/0000-0001-7281-4853)
Institutions
- Central South University (CN)
- Chinese PLA General Hospital (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Hunan Children's Hospital (CN)
- Shenzhen Bao'an District People's Hospital (CN)
- Shenzhen Children's Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Intensive Care Medicine Experimental
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1186/s40635-025-00822-z
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00