Cannabinoid type 1 receptors in the mice prefrontal cortex regulate object location memory acquisition via GABAergic neurons
Our findings suggest that CB1Rs in the PFC are involved in memory acquisition through the regulation of GABA release, offering new insights into how cannabis use lead to cognitive impairment.
Authors
- Shin‐ichi Muramatsu (ORCID: https://orcid.org/0000-0002-3185-7790)
- Jun Yokose (ORCID: https://orcid.org/0000-0002-1953-9378)
- Yuki Shigetsura (ORCID: https://orcid.org/0000-0001-7033-5357)
- Atsumi Nitta (ORCID: https://orcid.org/0000-0001-6916-9160)
- Tomohiro Tokutake
- Yusuke Yano
Institutions
- Jichi Medical University (JP)
- Kyoto University Hospital (JP)
- University of Toyama (JP)
- Tohoku Medical and Pharmaceutical University (JP)
Publication Details
- Journal
- Behavioral and Brain Functions
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1186/s12993-025-00306-w
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jichi Medical University
- Japan Society for the Promotion of Science