Preclinical evaluation of Lactiplantibacillus plantarum as a probiotic alternative against multidrug-resistant avian pathogenic Escherichia coli in chickens
<i>L. plantarum</i> ATS1 provides protective and immunomodulatory effects against APEC by supporting intestinal colonization, surviving in macrophages, and enhancing humoral immunity. These findings highlight its potential as a probiotic strategy to improve broiler health and reduce dependence on antibiotics.
Authors
- Hanem El-Sharkawy (ORCID: https://orcid.org/0000-0002-4376-732X)
- Yamen Hegazy (ORCID: https://orcid.org/0000-0002-7355-8238)
- Hussein Babiker (ORCID: https://orcid.org/0000-0003-2051-4423)
- Ahmed M. Abdelsalam (ORCID: https://orcid.org/0000-0001-6148-6524)
- Amin Tahoun (ORCID: https://orcid.org/0000-0002-9239-622X)
- Mohamed Marzok (ORCID: https://orcid.org/0000-0002-7961-1247)
Institutions
- Kafrelsheikh University (EG)
- Jordan University of Science and Technology (JO)
- The University of Texas at San Antonio Health Science Center (US)
- Médecins Sans Frontières (JO)
- King Faisal University (SA)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3389/fimmu.2025.1640600
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- King Faisal University