Novel cytomegalovirus variants in immunocompromised hosts: genetic insights and clinical significance
Interpreting cytomegalovirus (HCMV) drug resistance mutations requires a comprehensive approach that integrates molecular data with clinical context. Early genotypic analysis can guide antiviral therapy; however, improved classification of mutations based on predicted resistance potential and phenotypic characteristics may optimize clinical decision-making. These insights emphasize the need for personalized management strategies in immunocompromised patients.
Authors
- Abdulrahman AlSweed (ORCID: https://orcid.org/0000-0003-0551-9322)
- Sami Al-Hajjar (ORCID: https://orcid.org/0000-0003-4664-9748)
- Fatimah S. Alhamlan (ORCID: https://orcid.org/0000-0003-1765-4310)
- Madain S. Alsanea (ORCID: https://orcid.org/0000-0001-8632-2040)
- Reem S. Almaghrabi (ORCID: https://orcid.org/0000-0002-1275-8324)
- Ahmed Ali Al-Qahtani (ORCID: https://orcid.org/0000-0003-4584-5739)
- Mohammad AlSuhaibani
Institutions
- Alfaisal University (SA)
- King Faisal Specialist Hospital & Research Centre (SA)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3389/fmicb.2025.1677054
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- King Faisal Specialist Hospital and Research Centre