Sevoflurane impairs neurogenesis and cognitive function by inhibiting fatty acid β-oxidation in neural stem/progenitor cells of neonatal rats
Sevoflurane impairs neurogenesis and cognitive function by suppressing FAO in NSPCs of the developing brain. Boosting FAO activity in NSPCs could be a potential strategy to prevent sevoflurane-induced cognitive deficits.
Authors
- Shuyue Zhang (ORCID: https://orcid.org/0009-0004-9324-2021)
- Liufei Yang (ORCID: https://orcid.org/0009-0009-0236-4522)
- Haodong Sun (ORCID: https://orcid.org/0000-0002-5847-3471)
- Peng Jia (ORCID: https://orcid.org/0000-0003-0110-3637)
- Xinlin Chen (ORCID: https://orcid.org/0000-0002-2650-8051)
- Yuying Lu
- Pei Fan (ORCID: https://orcid.org/0000-0002-6512-5731)
- Haidong Wei
- Yuanyuan Zhang (ORCID: https://orcid.org/0000-0002-1845-7725)
- Kui Wang (ORCID: https://orcid.org/0000-0003-3503-1563)
- Yong Liu (ORCID: https://orcid.org/0000-0003-1278-7114)
- Ning Wang (ORCID: https://orcid.org/0000-0001-9757-3291)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-8561-5092)
- Pengbo Zhang (ORCID: https://orcid.org/0000-0002-8822-2868)
- Haixia Lu
- Yiqin Cheng
Institutions
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Chinese Medical Journal
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1097/cm9.0000000000003864
- Citations
- 1
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 1.32