MiR-4664-3p as a potential diagnostic, prognostic, and immunotherapeutic biomarker in NSCLC: modulation of tumor progression through CD8 + T cell regulation
These results suggest that the miR-4664-3p/PRKCB axis is crucial in NSCLC progression and immune modulation. Hence, MiR-4664-3p is a potential diagnostic and prognostic indicator, as well as therapeutic target in immunotherapy strategies for NSCLC.
Authors
- Yan Su (ORCID: https://orcid.org/0000-0002-3815-6663)
- Qianqian Guo (ORCID: https://orcid.org/0000-0002-6313-8854)
- Cong Gao (ORCID: https://orcid.org/0000-0002-5673-9723)
- Linzhu Lu
- Chun Yi (ORCID: https://orcid.org/0000-0003-3506-2781)
- Jing Lü (ORCID: https://orcid.org/0000-0002-1684-9258)
- Yun-long Zhao (ORCID: https://orcid.org/0009-0008-9342-9207)
- Hao Zhang (ORCID: https://orcid.org/0000-0002-0045-8404)
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Hunan Provincial Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3389/fonc.2025.1642999
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00