Procalcitonin-guided antibiotic therapy in elderly ICU patients with severe pneumonia: a retrospective analysis of biomarker dynamics
This study indicates that PCT-guided antibiotic therapy may optimize treatment strategies, potentially improve clinical outcomes, and enhance antibiotic stewardship in elderly ICU patients with severe pneumonia. Further studies are needed to establish optimal PCT cutoff values and evaluate its combined use with other biomarkers.
Authors
- Xuehui Liu (ORCID: https://orcid.org/0000-0002-1604-0133)
- Wen Li (ORCID: https://orcid.org/0000-0002-1747-9594)
- R C Chen (ORCID: https://orcid.org/0000-0001-7076-619X)
Institutions
- China Railway Group (China) (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3389/fmed.2025.1656909
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00