Time-dependent relationship between urinary biomarkers of nucleic acid oxidation and colorectal cancer risk
This novel finding of a time-dependent inverse relationship between systemic oxidative stress and CRC risk, if further confirmed, may prompt a reevaluation of redox-based chemoprevention strategies.
Authors
- Qiuyin Cai (ORCID: https://orcid.org/0000-0002-9384-5648)
- Qingxia Chen (ORCID: https://orcid.org/0000-0003-0507-1847)
- Gong Yang
- Ginger L. Milne (ORCID: https://orcid.org/0000-0003-3890-151X)
- Marina Sayuri Nogueira (ORCID: https://orcid.org/0000-0001-8092-928X)
- Yingya Zhao
- Qing Lan (ORCID: https://orcid.org/0000-0001-7791-5020)
- Nathaniel Rothman (ORCID: https://orcid.org/0000-0001-6924-0895)
- Wei Zheng (ORCID: https://orcid.org/0000-0003-1226-070X)
- Xiao-Ou Shu
- Yu-Tang Gao
Institutions
- Renji Hospital (CN)
- Shanghai Cancer Institute (CN)
- National Cancer Institute (US)
- Division of Cancer Epidemiology and Genetics
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- JNCI Journal of the National Cancer Institute
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1093/jnci/djaf312
- Primary Topic
- Antioxidant Activity and Oxidative Stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00