Melatonin inhibits ferroptosis in myocardial ischemia/reperfusion injury by inhibiting the ATM/p53 signaling pathway
These findings suggest that melatonin pretreatment protects cardiomyocytes from I/R injury by inhibiting cell ferroptosis via suppression of the ATM/p53 signaling pathway.
Authors
- Ting Zhao (ORCID: https://orcid.org/0000-0003-3502-6043)
- Shengqiang Li (ORCID: https://orcid.org/0000-0001-5755-9495)
- Xiulan Su (ORCID: https://orcid.org/0000-0003-4147-4678)
- Di Wang (ORCID: https://orcid.org/0000-0003-0870-2157)
- Peng Zhāng (ORCID: https://orcid.org/0000-0003-2039-9373)
- Yan Dong (ORCID: https://orcid.org/0000-0003-1223-881X)
- Peng Wang (ORCID: https://orcid.org/0000-0003-3047-1666)
- Zhen Lv
Institutions
- The Fourth People's Hospital of Zibo City (CN)
- Integrated Chinese Medicine (China) (HK)
- Second Hospital of Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Central Hospital of Zibo (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Redox Report
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1080/13510002.2025.2583802
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00