Critical Analysis Of The Study On Vitamins And Dental Caries

This study aims to investigate the relationship between vitamin intake and the occurrence of dental caries. This study was a retrospective study that collected data from the NHANES database from 2011 to 2018. The number of dental caries teeth was determined using the Radike AW caries diagnostic criteria (1968), and vitamin consumption data were obtained through face-to-face interviews. Logistic regression analysis was used to explore the association between dental caries and vitamins, and variables with P < 0.1 in the univariate analysis were selected for multivariate logistic regression analysis. Clinical prediction models were constructed for variables with P < 0.05 and internally and externally validated to assess the predictive ability of the models. This study included 4,221 subjects (2,215 training, 2,006 validation), with vitamin C (47.6%), vitamin K (19.4%), vitamin B12, (14.2%), and vitamin D(11.3%) demonstrating the highest intake proportions. Logistic regression identified age, education, vitamin D, and vitamin K as predictors of dental caries, while the clinical model exhibited consistent moderate predictive performance across both datasets. Results remained stable after variable incorporation, confirming model reliability. Dental caries correlate with vitamin D excess and K deficiency, requiring further clinical trials to confirm mechanisms.