MICRR: A Rare Case Report With 4-Year Follow-Up

MICRR (Multifocal Idiopathic Cervical Root Resorption) is a rare external root resorption characterized by rarity and progression. Its etiology remains unclear, occurring without caries, trauma, or orthodontic history. The pathology progresses from localized degradation to pulpal involvement and eventual extraction. A 4-year follow-up was conducted on a 34-year-old male patient. Most of teeth were discovered incidentally as residual roots or mobile teeth. We ruled out possible causes such as trauma, orthodontic treatment, and systemic diseases. Based on the CBCT images of “apple-core" like resorption at the cementoenamel junction, he was diagnosed with MICRR. To address restore functional occlusion, after extracted, ITI immediate implants with healing abutments were placed into the extraction sockets. Concurrently, guided bone regeneration (GBR) was performed using DBBM(Bio-Oss®) and a resorbable membrane (Bio-Gide®) to optimize the peri-implant hard tissue architecture. At 6 months post-implantation, impressions were obtained for prosthetic restoration. Future research should delve into the underlying etiology of idiopathic conditions, such as abnormal gene expression regulation and local microenvironment imbalance. Currently, CBCT is an accurate method for early diagnosis. There is an urgent need to explore a biomarker detection combining salivary proteomics and serum microRNA profiling for early screening, providing opportunities for tooth preservation. It highlights that MICRR can occur in populations without established risk factors, necessitating heightened clinical vigilance. It underscores FDI’s call for global research collaboration to unravel the pathogenesis of rare dental diseases.