Psychological Factors And Quality Of Life On Oral Mucosal Diseases

This study aims to explore the psychological issues in patients with recurrent aphthous ulcer (RAU), oral lichen planus (OLP), oral leukoplakia (OLK), and oral submucous fibrosis (OSF), as well as their impact on oral health-related quality of life (OHRQoL). This study included 229 patients with clinically diagnosed oral mucosal diseases from January to December 2023. There were 55 RAU, 68 OLK, 50 OLP, and 56 OSF patients. Socio - demographic info, VAS, OHIP - 5, and DASS - 21 scales were used to statistically analyze patients' psychological problems and quality of life. There were 229 valid questionnaires collected, consisting of 83 females and 146 males with a mean age of 45.24 (SD = 11.88) years. Multiple regressions between DASS-21 scores and OHIP-5 scores revealed generally negative impacts of psychological problems on OHRQoL, with depression on OLP (β =0.47), OLK (β = 0.65) and OSF (β =0.38), stress on RAU (β =0.29), OLP (β = 0.72), OLK (β =0.38) and OSF (β =0.60), and anxiety on OLP (β =0.33), OLK (β = 0.49) and OSF (β =0.51). Psychological issues such as depression, stress, and anxiety in patients with oral mucosal diseases significantly impact their quality of life, thereby influencing disease prognosis and outcomes. By utilizing shorter, more convenient, and effective psychological and quality-of-life questionnaires in clinical practice, healthcare providers can better identify patient needs and develop precise prevention and treatment strategies, ultimately improving patients' quality of life.