Comparing 0.75% Ropivacaine Versus 2% Lidocaine In Im3m Extractions

This study aimed to compare the analgesic efficacy of 0.75% ropivacaine versus 2% lidocaine following the extraction of impacted mandibular third molars and their effects on oral health-related quality of life (OHRQoL). The findings may provide a reference for the personalized selection of local anesthetics based on extraction difficulty and for improving postoperative OHRQoL A total of 149 patients treated at our hospital between October 2021 and October 2022 were randomly assigned to either the experimental group (n=73, 0.75% ropivacaine) or the control group (n=76, 2% lidocaine) for local anesthesia. The experimental group demonstrated significantly superior outcomes in anesthesia quality, postoperative analgesia duration, anesthesia duration, and time to first analgesic intake (P<0.01). Additionally, the experimental group showed significantly better postoperative pain scores, reduced analgesic consumption, and improved OHRQoL scores (P<0.01), particularly in moderately difficult extractions. In high-difficulty cases, the experimental group also outperformed the control group in reducing analgesic use and enhancing postoperative social and psychological well-being. 0.75% ropivacaine provides better postoperative analgesia and greater improvement in OHRQoL compared to 2% lidocaine, making it particularly suitable for moderately to highly difficult extractions and patients prioritizing postoperative quality of life.

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Publication Details

Journal
International Dental Journal
Published
2025-10-01
DOI
https://doi.org/10.1016/j.identj.2025.105898
Primary Topic
Dental Anxiety and Anesthesia Techniques
Type
article
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article

Comparing 0.75% Ropivacaine Versus 2% Lidocaine In Im3m Extractions

Kun Bu, Huajie Zou, Simin Zhou
International Dental Journal
Dental Anxiety and Anesthesia Techniques
article

Comparing 0.75% Ropivacaine Versus 2% Lidocaine In Im3m Extractions

Kun Bu, Huajie Zou, Simin Zhou
article en

Abstract

This study aimed to compare the analgesic efficacy of 0.75% ropivacaine versus 2% lidocaine following the extraction of impacted mandibular third molars and their effects on oral health-related quality of life (OHRQoL). The findings may provide a reference for the personalized selection of local anesthetics based on extraction difficulty and for improving postoperative OHRQoL A total of 149 patients treated at our hospital between October 2021 and October 2022 were randomly assigned to either the experimental group (n=73, 0.75% ropivacaine) or the control group (n=76, 2% lidocaine) for local anesthesia. The experimental group demonstrated significantly superior outcomes in anesthesia quality, postoperative analgesia duration, anesthesia duration, and time to first analgesic intake (P<0.01). Additionally, the experimental group showed significantly better postoperative pain scores, reduced analgesic consumption, and improved OHRQoL scores (P<0.01), particularly in moderately difficult extractions. In high-difficulty cases, the experimental group also outperformed the control group in reducing analgesic use and enhancing postoperative social and psychological well-being. 0.75% ropivacaine provides better postoperative analgesia and greater improvement in OHRQoL compared to 2% lidocaine, making it particularly suitable for moderately to highly difficult extractions and patients prioritizing postoperative quality of life.

International Dental JournalVol. 75
Nanchang University (CN), Second Affiliated Hospital of Nanchang University (CN), The First People's Hospital of Guiyang (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Openalex Percentile: Top 54%
Dental Anxiety and Anesthesia Techniques
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