Case Report Of Dentinogenesis Imperfecta

Dentinogenesis imperfecta is an autosomal-dominant genetic disorder characterized by marked aberrations in dentin mineralization and disorganized dentin architecture. This condition typically manifests across successive generations within a family. A 24-year- old female patient who was referred from an external hospital for treatment consultation. Six months prior, during root canal treatment at the referring hospital, pulp calcification in multiple teeth and periapical inflammation were detected, prompting her to seek further care at our institution.​ Upon clinical examination, enamel hypoplasia was observed in the lower anterior teeth. Tooth 46 had undergone prior restoration-related preparation, exhibiting grade II mobility with a palpable root furcation. CBCT imaging demonstrated obscured root canal images throughout the dentition, along with the presence of low-density lesions at the apices of teeth 14, 15, 16, 26, 35, 36, and 46. Pathological evaluation confirmed a diagnosis of chronic periapical periodontitis. Based on the comprehensive assessment, the patient was clinically diagnosed with hereditary dentinogenesis imperfecta accompanied by pulp calcification throughout the mouth. The proposed treatment plan included root canal therapy in combination with inlay, full-crown, or post-crown restorations, with extraction being considered when necessary. Notably, the patient's grandmother, mother, and aunt all displayed similar dental symptoms. The intra-oral examination findings, crown morphological features, and panoramic radiograph results in this case were highly congruent with the typical characteristics of dentinogenesis imperfecta.