Analysis Of Off-Label Medication Use For Oral Mucosal Diseases

By analyzing the situation of off-label medication in outpatient patients with oral mucosal disease, this study can provide scientific basis for the standardization and individualized treatment of outpatient medication in mucosal department, and promote the safety and effectiveness of clinical medication. Retrospective statistics and analysis were made on the prescription of outpatient patients of a dental hospital in Guizhou Province from January to December 2023. Patients with oral mucosal diseases used 59 drugs with 16,180 drugs, with off-label drugs at 41.06%. 15 outpatient patients had off-label drugs, accounting for 25.42% of the total drugs. Among them, 8 kinds of drugs are off-indications, and the other 7 kinds are ultra-indications or over-indications and over-usage and dosage. All types of off-label drugs were calculated according to the number of medication items, off-indication (27.21%), over-indication and over-usage (72.79%). It is common for patients with oral mucosal disease. The formulation and improvement of norms and standards for off-label drugs is of great significance for improving medical quality, ensuring patient safety, promoting rational drug use and promoting the development of the pharmaceutical industry. It also provides scientific basis for the standardization and individualized treatment of outpatient drugs in mucosal department, and promotes the safety and effectiveness of clinical drug use.