Perioperative Management Of Anticaogulated Patients In Oral Surgery: Tranexamic Acid

Managing anticoagulated patients in oral surgery requires balancing bleeding risk with thromboembolic prevention. Discontinuing anticoagulants increases thrombotic risk, while maintaining them may lead to excessive bleeding. Topical 4.8% tranexamic acid (TXA), an antifibrinolytic agent, stabilizes clot formation without affecting systemic coagulation. This case highlights the use of TXA as a local hemostatic measure in an anticoagulated patient undergoing tooth extraction for implant placement. A male patient on anticoagulants required extraction before dental implant placement. • Preoperative: No anticoagulation adjustment; TXA rinse (4.8%, 2 min). • Intraoperative: Atraumatic extraction, Gentle irrigation with TXA, TXA-soaked gauze applied. • Postoperative: TXA mouth rinses (10 mL, 2 min, 4×/day for 2 days). Follow-ups at 24 hours, 1 week, and 2 weeks. Hemostasis was achieved without excessive bleeding or complications. Topical TXA effectively controlled bleeding while allowing continuous anticoagulation, aligning with current evidence-based guidelines. Studies support TXA’s role in reducing oral surgery bleeding without systemic risks. 4.8% TXA is a safe, effective hemostatic adjunct for anticoagulated patients undergoing oral surgery. Its use eliminates the need for anticoagulant discontinuation, minimizing both thrombotic and bleeding risks. This case supports TXA as a standard hemostatic strategy in oral surgery, warranting further study.

Authors

Institutions

Publication Details

Journal
International Dental Journal
Published
2025-10-01
DOI
https://doi.org/10.1016/j.identj.2025.105835
Primary Topic
Blood transfusion and management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Perioperative Management Of Anticaogulated Patients In Oral Surgery: Tranexamic Acid

Mark E Perry, Sandra Ammonn
International Dental Journal
Blood transfusion and management
article

Perioperative Management Of Anticaogulated Patients In Oral Surgery: Tranexamic Acid

Mark E Perry, Sandra Ammonn
article en

Abstract

Managing anticoagulated patients in oral surgery requires balancing bleeding risk with thromboembolic prevention. Discontinuing anticoagulants increases thrombotic risk, while maintaining them may lead to excessive bleeding. Topical 4.8% tranexamic acid (TXA), an antifibrinolytic agent, stabilizes clot formation without affecting systemic coagulation. This case highlights the use of TXA as a local hemostatic measure in an anticoagulated patient undergoing tooth extraction for implant placement. A male patient on anticoagulants required extraction before dental implant placement. • Preoperative: No anticoagulation adjustment; TXA rinse (4.8%, 2 min). • Intraoperative: Atraumatic extraction, Gentle irrigation with TXA, TXA-soaked gauze applied. • Postoperative: TXA mouth rinses (10 mL, 2 min, 4×/day for 2 days). Follow-ups at 24 hours, 1 week, and 2 weeks. Hemostasis was achieved without excessive bleeding or complications. Topical TXA effectively controlled bleeding while allowing continuous anticoagulation, aligning with current evidence-based guidelines. Studies support TXA’s role in reducing oral surgery bleeding without systemic risks. 4.8% TXA is a safe, effective hemostatic adjunct for anticoagulated patients undergoing oral surgery. Its use eliminates the need for anticoagulant discontinuation, minimizing both thrombotic and bleeding risks. This case supports TXA as a standard hemostatic strategy in oral surgery, warranting further study.

International Dental JournalVol. 75
Emmanuel Bible College (CA), Huntington Society of Canada (CA)
Openalex Percentile: Top 68%
Blood transfusion and management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.