Innovative Restorative Protocol For Irreversible Pulpitis: A 3-Year Study

This study presents the "Pulpitis Restorative Protocol" (PRP), a novel approach for managing deep caries with reversible pulpitis (RP) and symptomatic irreversible pulpitis (IP) using standard restorative materials. PRP offers a high success rate and minimal post-operative pain, providing a more conservative and simpler IP treatment alternative to endodontic treatment. This prospective case series treated 25 patients with PRP (15 IP, 10 RP), with follow-up from 3 to 36 months (5 cases 3-11 months, 12 cases 12-23 months and 8 cases 24-36 months). Clinical success was achieved in 13 of 15 IP cases and 9 of 10 RP cases. At 24 hours post-treatment, all patients—and 92% on the same night—reported little or no pain without analgesics PRP employs a combination of glutaraldehyde and resin-modified glass ionomer (RMGI) in an alkaline environment which may activates glutaraldehyde’s protein cross-link activity to sterilize dental cavity, denature the bacterial toxin and inflammatory factors, exert its apoptosis effect on necrotic pulp tissue adjacent to caries to eliminate pulp inflammation and accomplish pain relief. PRP is a simple, affordable alternative for managing symptomatic IP, especially in emergency or rural settings with limited endodontic access. Applicable to both RP and IP, it offers rapid pain relief, reducing the need for analgesics and the risk of narcotic misuse. PRP may also prevent post-restorative pain in deep caries or serve as a temporary measure. Its effectiveness and broad potential warrant further validation through randomized clinical trials