Gdooh Sub-Nanowires As Primer For Enhancing Dentin Bonding Stability

Sub-nanowires exhibits characteristic size similar to both organic macromolecule and inorganic unit cell. Meanwhile, the high surface atom ratio of sub-nanowires provides multiple sites for the interaction with substrate, showing stable underwater bonding performance. Here, we fabricate Gadolinium hydroxylase sub-nanowires (GdOOH-SNWs) in colloidal state as primer to enhance the dentin bonding stability. GdOOH-SNWs was fabricated through synthetic method with oleamine ligands. Then, we designed GdOOH-ethanol solution as primer. Transmission electron microscope (TEM) was used to evaluate the dispersibility of GdOOH. Thermocycling test, enzyme-aging test and the elastic modulus of resin-dentin bonding interface evaluation were conducted to confirm the effect of GdOOH-SNWs on the stability of resin-dentin interface. The diameter of GdOOH-SNWs is less than 1 nm. It exhibits fluid viscous colloid state, similar to the resin matrix. Furthermore, it shows good dispersibility in ethanol. The resin-dentin hybrid layer exhibits about 1.5 times higher elastic modulus compared to the control group (p < 0.05). Also, the stability of resin-dentin bonding interface show significant enhancement when it is pretreated by GdOOH-SNWs compared to the control group (p < 0.05). GdOOH-SNWs with fluid viscous colloid state is a promising material in sub-nanoscale for enhancing dental bonding stability. This research highlights the bio-application potential of materials in sub-nanoscale.