Aloe Vera Probiotic Fermentation Inhibits The Progression Of Oral Mucositis
To investigated the ameliorative effect of Aloe vera probiotic fermentation on oral mucositis caused by radiotherapy and delved into the molecular mechanism of its action 1.Aloe Vera Fermentation Solution Preparation. 2. Development of OM Rat Model and Treatment. The results demonstrated that Aloe vera probiotic fermentation ameliorates radiotherapy-induced oral mucositis and attenuates pathological damage and apoptosis via the PI3K/AKT/FoXO1 signaling pathway. It can also regulate oral and intestinal flora dysbiosis. The results demonstrated that Aloe vera probiotic fermentation ameliorates radiotherapy-induced oral mucositis and attenuates pathological damage and apoptosis via the PI3K/AKT/FoXO1 signaling pathway. It can also regulate oral and intestinal flora dysbiosis.
Authors
- Xiufen Wang (ORCID: https://orcid.org/0000-0002-3541-740X)
- Ruyue Chen (ORCID: https://orcid.org/0000-0002-0847-4740)
Institutions
- Nanchang University (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.identj.2025.104769
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00