Enucleation Combined Guided Bone Regeneration In Odontogenic Cysts: Case Report

This case report demonstrates the efficacy of surgical enucleation combined with guided bone regeneration (GBR) in treating an odontogenic cyst. A 46-year-old male came with discomfort in the right maxilla. Clinical examination revealed palpable bony expansion with intact overlying mucosa. Cone beam computed tomography (CBCT) identified a unilocular radiolucency (15×23×13mm) encircling an unerupted supernumerary teeth. The cyst was enucleated via a full-thickness flap, with the supernumerary tooth extracted. The bony defect was filled with a total of 1.5g xenograft bone (Bio-Oss, Geistlich, Switzerland). A resorbable collagen membrane (HEAL-ALL, ZH-BIO, China) was trimmed to cover both the inner aspect of the defective bony wall and the surface of the bone graft. Primary closure was achieved using non-resorbable 4-0 Mersilk sutures. Histopathology confirmed the diagnosis of dentigerous cyst. Post-operative CBCT at 3 months observed that the bone defect healed well with obvious bone tissue regeneration. At 6 months, radiographic follow-up revealed continued osteogenesis and stable periodontal soft tissue healing. Dentigerous cysts, typically associated with impacted teeth, require timely intervention to prevent pathologic fractures or tooth displacement. While enucleation remains standard for small-to-moderate cysts, combining it with GBR enhances bone healing by isolating the defect and promoting osteoblast activity. This approach minimizes infection risks and accelerates functional restoration. Enucleation with GBR offers a reliable treatment for odontogenic cysts, exhibiting enhanced osteogenic capability and reducing postoperative morbidity.