Clinical Study Of Dentin Matrix For Ridge Preservation

Exploring the effectiveness of autologous partially demineralised dentin matrix as a bone grafting material in post-extraction ridge preservation. Fifty cases of extracted teeth were selected and randomly divided into APDDM group and control group (25 cases each). In the APDDM group, the extracted teeth were processed into dentin particles, and then grafted into the extraction sockets, and the wounds were covered with resorbable collagen membranes and closed with sutures; the control group was transplanted with Bio-Oss bone powder in the extraction sockets, and the rest of the treatment was the same as that of the APDDM group. CBCT was taken immediately, 3 months and 6 months after surgery to evaluate the changes in alveolar socket width and height. Bone tissue samples were collected at 8 months postoperatively for immunohistochemical staining analysis. The CBCT results at the immediate, 3-month and 6-month postoperative periods showed no statistically significant differences in the width and height of the extraction sockets in the control group compared with the APDDM group (P > 0.05). Immunohistochemical staining showed that SATB2 was expressed in fibrotic tissues of both APDDM and control groups, and there was no statistically significant difference in the expression level of SATB2. In the both group, new bone was formed gradually, and the arrangement of osteoblasts tended to be regular. Dentin matrix as a ridge preserved implant material was effective in maintaining the width and height of extraction sockets with similar results to the control group.