Eosinophilic Granulomatosis With Polyangiitis (EGPA) With Tooth Lose

This case report details the management of dental complications in an 11-year-old male diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA), a rare systemic vasculitis. This case highlights specific oral features of EGPA in pediatric patients, which have not been reported in detail in previous literature. Therefore, this case is of great significance for the study of EGPA and tooth loss in children. The patient exhibited persistent miliary papules, progressive tooth loss, and episodic facial swelling. Clinical examination revealed extensive alveolar bone resorption and advanced periodontitis. Laboratory findings, which confirmed eosinophilia and elevated inflammatory markers, corroborated the diagnosis of EGPA along with imaging data. Treatment included the extraction of loose teeth and the provision of transitional dentures, with plans for subsequent definitive prosthetic rehabilitation. Due to the severely low and flat alveolar bone, conventional full dentures were unsuitable because they could not achieve proper positioning and stability. Therefore, the Biofunctional Prosthetic System (BPS) denture restoration was employed. The intervention significantly improved the patient’s oral functionality and aesthetic appearance. The patient only left three teeth with grade 3 tooth mobility. The root was absorbed to 1/3 of the root tip. Since they had no retention value, we extracted them. The BPS adheres effectively to the patient’s mandibular alveolar bone, addressing the limitation of ordinary dentures. The case report highlights the importance of recognizing and managing the oral features of rare disease EGPA, showcasing the value of innovative prosthodontic technique BPS denture restoration and interdisciplinary collaboration in stomatology.