Multifaceted “composite” actin nucleator orchestrates polymerization via dynamic assembly

In this issue, Magliozzi et al. (https://doi.org/10.1083/jcb.202505039) describe a novel actin nucleation mechanism involving an Aip5-Bud6-Bni1 "composite nucleator," which binds both the formin-mediated barbed end and Aip5-associated pointed end, enabling coordinated filament elongation and maintaining actin cable thickness.

Authors

Institutions

Publication Details

Journal
The Journal of Cell Biology
Published
2025-10-16
DOI
https://doi.org/10.1083/jcb.202509234
Primary Topic
Cellular Mechanics and Interactions
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Multifaceted “composite” actin nucleator orchestrates polymerization via dynamic assembly

Yansong Miao, Jiecai Han
The Journal of Cell Biology
Cellular Mechanics and Interactions
article

Multifaceted “composite” actin nucleator orchestrates polymerization via dynamic assembly

Yansong Miao, Jiecai Han
article en

Abstract

In this issue, Magliozzi et al. (https://doi.org/10.1083/jcb.202505039) describe a novel actin nucleation mechanism involving an Aip5-Bud6-Bni1 "composite nucleator," which binds both the formin-mediated barbed end and Aip5-associated pointed end, enabling coordinated filament elongation and maintaining actin cable thickness.

The Journal of Cell BiologyVol. 224(12)
Nanyang Technological University (SG)
Ministry of Education, India
Openalex Percentile: Top 66%
Cellular Mechanics and Interactions
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.