<i>Lactobacillus gasseri</i> TF08-1 ameliorates high-fat diet induced nonalcoholic fatty liver disease and regulates gut microbiota in mice
Lactobacillu gasseri TF08-1 demonstrates probiotic efficacy against NAFLD through dual mechanisms: direct metabolic modulation and gut microbiota restoration. The lipid metabolism capacity encoded by its genome likely contributes to therapeutic effects.
Authors
- Liang Xiao
- Zizhen Yang (ORCID: https://orcid.org/0009-0000-8455-9749)
- Y X Zou
- Shangyong Li (ORCID: https://orcid.org/0000-0001-7408-556X)
- Yiyi Zhong
- Ningning He (ORCID: https://orcid.org/0000-0001-9453-6911)
- Qianyue Xu (ORCID: https://orcid.org/0009-0000-5819-6892)
- Bei Liu (ORCID: https://orcid.org/0000-0003-2155-2974)
- Haifeng Zhang (ORCID: https://orcid.org/0000-0001-8967-8173)
- Haoyu Wang (ORCID: https://orcid.org/0000-0001-6647-598X)
- Qiang Luo (ORCID: https://orcid.org/0000-0002-9062-4364)
- Zhinan Wu
- Yu Tian (ORCID: https://orcid.org/0000-0001-5367-7515)
Institutions
- BGI Group (China) (CN)
- Qingdao University (CN)
- Northwest University (US)
- Northwest University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Botswana Geoscience Institute (BW)
- MD Precision (Canada) (CA)
- University of Chinese Academy of Sciences (CN)
- BGI Research (CN)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1093/jambio/lxaf271
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81