Nuclear factor E2 p45-related factor (NRF2) and peroxiredoxin 6 tissular expression as prognostic biomarkers for advanced HPV-negative squamous cell carcinoma of the oropharynx

Elevated expression levels of peroxiredoxin 6, either alone or in combination with NRF2, are poor prognostic indicators for patient survival.

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Publication Details

Journal
Translational Oncology
Published
2025-11-03
DOI
https://doi.org/10.1016/j.tranon.2025.102595
Primary Topic
Redox biology and oxidative stress
Type
article
Field-Weighted Citation Impact
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article

Nuclear factor E2 p45-related factor (NRF2) and peroxiredoxin 6 tissular expression as prognostic biomarkers for advanced HPV-negative squamous cell carcinoma of the oropharynx

Gersende Alphonse, Claire Rodriguez‐Lafrasse, Andreas Kobler, Nazim Benzerdjeb et al.
Translational Oncology
Redox biology and oxidative stress
article

Nuclear factor E2 p45-related factor (NRF2) and peroxiredoxin 6 tissular expression as prognostic biomarkers for advanced HPV-negative squamous cell carcinoma of the oropharynx

Gersende Alphonse, Claire Rodriguez‐Lafrasse, Andreas Kobler, Nazim Benzerdjeb, Anne‐Sophie Wozny, Mickaël Burgy, Alain C. Jung, Mamadou Soumboundou, Philippe Céruse, Céline Malésys, Pierre Philouze
article en

Abstract

Elevated expression levels of peroxiredoxin 6, either alone or in combination with NRF2, are poor prognostic indicators for patient survival.

Translational OncologyVol. 63
Université Claude Bernard Lyon 1 (FR), Centre National de la Recherche Scientifique (FR), Lyon College (US), Hôpital de la Croix-Rousse (FR), Institut de Cancérologie Strasbourg (FR), Gefluc Languedoc Roussillon (FR), Hospices Civils de Lyon (FR), Hôpital Lyon Sud (FR), Institute of Biophysics (BG)
Openalex Percentile: Top 71%
Redox biology and oxidative stress
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Nuclear factor E2 p45-related factor (NRF2) and peroxiredoxin 6 tissular expression as prognostic biomarkers for advanced HPV-negative squamous cell carcinoma of the oropharynx — Gersende Alphonse, Claire Rodriguez‐Lafrasse, et al. · Translational Oncology (2025) | TGRS Research Map | TGRS