Early Postoperative Decline in Insulin-Like Growth Factor 1 (IGF-1) Predicts Surgical Remission of Acromegaly
The degree of IGF-1 decline within days of pituitary surgery predicts 3-month acromegaly remission. Our findings argue for IGF-1 measurement before discharge to inform patient counseling during the surgical admission and guide intensity of early follow-up.
Authors
- Alkis J. Psaltis (ORCID: https://orcid.org/0000-0003-2967-1855)
- Wayne Rankin (ORCID: https://orcid.org/0000-0002-4427-9547)
- Alistair Jukes (ORCID: https://orcid.org/0000-0002-6363-1366)
- Sunita M C De Sousa (ORCID: https://orcid.org/0000-0003-0127-6482)
- Nicholas G. Candy (ORCID: https://orcid.org/0000-0002-8826-1840)
- Stephen Santoreneos
- Edward Mignone (ORCID: https://orcid.org/0009-0007-8605-0525)
- Christopher D. Ovenden (ORCID: https://orcid.org/0000-0001-8075-7852)
- David J. Torpy (ORCID: https://orcid.org/0000-0002-5069-0981)
- Ian Chapman
Institutions
- Royal Adelaide Hospital (AU)
- Flinders Medical Centre (AU)
- Queen Elizabeth Hospital (AU)
- The University of Adelaide (AU)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1016/j.wneu.2025.124611
- Citations
- 1
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.29