A case report of pancreatic lymphoepithelial cyst

PLEC, a rare benign lesion, often mimics malignancy, potentially leading to unnecessary radical surgeries. Diagnostic hallmarks include its tendency to present as an exophytic cystic mass in middle-aged men; CT features demonstrating cyst fluid density exceeding that of simple or mucinous cysts with thin, mildly enhancing walls; and pathognomonic magnetic resonance imaging findings of T2-hyperintense subcapsular nodules exhibiting restricted diffusion in a noninfiltrative, wall-apposed pattern without ductal communication. Markedly elevated CA19-9 levels should not preclude PLEC. When this constellation of features is present, PLEC should be considered in the differential diagnosis.