In vitro characterization of delafloxacin activity against intracellular Legionella: Exploring new treatment options for Legionnaires’ disease

Based on the results obtained, the higher intracellular activity of delafloxacin compared with levofloxacin and its better safety profile should be confirmed in phase IV clinical real-life cases of Legionnaires' disease.

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Publication Details

Journal
International Journal of Infectious Diseases
Published
2025-11-03
DOI
https://doi.org/10.1016/j.ijid.2025.108165
Primary Topic
Legionella and Acanthamoeba research
Type
article
Field-Weighted Citation Impact
0.00

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article

In vitro characterization of delafloxacin activity against intracellular Legionella: Exploring new treatment options for Legionnaires’ disease

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International Journal of Infectious Diseases
Legionella and Acanthamoeba research
article

In vitro characterization of delafloxacin activity against intracellular Legionella: Exploring new treatment options for Legionnaires’ disease

Nieves Sopena, María Luisa Pedro-Botet, Esteban Reynaga, Sara Quero, Noemí Párraga-Niño, Elisenda Arqué, Roger Cortès-Tarragó, Javier Díez de los Ríos, Lluc Vinyeta, Maria Basart Altieri, Sarahi Marieliza Elizondo
article en

Abstract

Based on the results obtained, the higher intracellular activity of delafloxacin compared with levofloxacin and its better safety profile should be confirmed in phase IV clinical real-life cases of Legionnaires' disease.

International Journal of Infectious DiseasesVol. 162
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (ES), Hospital Universitari Germans Trias i Pujol (ES)
Centres de Recerca de Catalunya, Generalitat de Catalunya, Universitat Autònoma de Barcelona, Instituto de Salud Carlos III
Openalex Percentile: Top 72%
Legionella and Acanthamoeba research
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