2025 American College of Rheumatology ( <scp>ACR</scp> ) Guideline for the Treatment of Systemic Lupus Erythematosus
This guideline presents direction regarding treatment and management of SLE and provides a foundation for well-informed, shared clinician-patient decision-making. These recommendations should not be used to limit or deny access to therapies, as treatment decisions may vary due to the unique clinical situation and personal preferences of each person with SLE.
Authors
- Laís Lopes Almeida Gomes (ORCID: https://orcid.org/0000-0001-5396-4362)
- Linda T. Hiraki (ORCID: https://orcid.org/0000-0002-6690-8148)
- Priyanka Chandrasekhar Iyer (ORCID: https://orcid.org/0000-0003-4863-5585)
- Marat Turgunbaev
- Mary Beth F. Son (ORCID: https://orcid.org/0000-0002-7394-2862)
- Benjamin F. Chong (ORCID: https://orcid.org/0000-0002-4092-7658)
- Kenneth Kalunian (ORCID: https://orcid.org/0000-0003-0261-3102)
- Alain Sánchez-Rodríguez (ORCID: https://orcid.org/0000-0001-5758-0542)
- Megan M. Lockwood (ORCID: https://orcid.org/0000-0001-8863-219X)
- Cynthia Aranow (ORCID: https://orcid.org/0000-0001-9299-0053)
- Vaidehi Chowdhary (ORCID: https://orcid.org/0000-0003-4626-2412)
- Muayad Azzam (ORCID: https://orcid.org/0000-0002-2046-8343)
- April Jorge (ORCID: https://orcid.org/0000-0001-6935-880X)
- Gabriel Figueroa‐Parra (ORCID: https://orcid.org/0000-0002-6077-8899)
- Hermine I. Brunner (ORCID: https://orcid.org/0000-0001-9478-2987)
- S.Psi. Taufik Kasturi (ORCID: https://orcid.org/0000-0001-8496-5595)
- Alí Duarte‐García (ORCID: https://orcid.org/0000-0003-1749-5719)
- Christie M. Bartels (ORCID: https://orcid.org/0000-0001-6523-0374)
- Victoria P. Werth (ORCID: https://orcid.org/0000-0003-3030-5369)
- Tamar B. Rubinstein (ORCID: https://orcid.org/0000-0001-8170-9377)
- Maria Dall’Era (ORCID: https://orcid.org/0000-0001-7439-2316)
- Kimberly DeQuattro (ORCID: https://orcid.org/0000-0001-8339-5666)
- Joanne S. Cunha
- Kimberly P. Liang (ORCID: https://orcid.org/0000-0002-5157-5467)
- Bonnie L. Bermas (ORCID: https://orcid.org/0000-0002-1007-4084)
- Shivani Garg (ORCID: https://orcid.org/0000-0001-7272-2692)
- María C. Cuéllar‐Gutiérrez (ORCID: https://orcid.org/0009-0008-0653-1386)
- Anna Broder (ORCID: https://orcid.org/0000-0003-4772-3057)
- Benjamin J. Smith (ORCID: https://orcid.org/0000-0002-6612-0473)
- Andrea Fava (ORCID: https://orcid.org/0000-0001-6738-4836)
- Peter Izmirly (ORCID: https://orcid.org/0000-0001-5445-2182)
- Jessica N. Williams (ORCID: https://orcid.org/0000-0002-1134-9625)
- Reem A. Mustafa (ORCID: https://orcid.org/0000-0002-2091-0875)
- Lisa R. Sammaritano (ORCID: https://orcid.org/0000-0003-2387-5363)
- Daniel J. Wallace (ORCID: https://orcid.org/0000-0002-2502-1372)
- Aimee O. Hersh (ORCID: https://orcid.org/0000-0002-8785-0010)
- Alexandra Legge (ORCID: https://orcid.org/0000-0003-0373-4985)
- Asha Thomas (ORCID: https://orcid.org/0000-0003-1058-8779)
- Amy S. Turner (ORCID: https://orcid.org/0000-0001-7695-2022)
- April Barnado (ORCID: https://orcid.org/0000-0002-9573-4335)
- Anca Askanase (ORCID: https://orcid.org/0000-0003-4597-5023)
- Diane L. Kamen (ORCID: https://orcid.org/0000-0002-7698-980X)
- Andrew Johannemann
- Hassan Kawtharany (ORCID: https://orcid.org/0009-0007-3725-8485)
- Natalie Smith
- Homa Timlin
- Jana Khawandi
- Marimee Jules
Institutions
- Florida State University (US)
- Hospital for Special Surgery (US)
- Cedars-Sinai Medical Center (US)
- American College of Rheumatology (US)
- Cincinnati Children's Hospital Medical Center (US)
- Boston Children's Hospital (US)
- Tufts Medical Center (US)
- Dalhousie University (CA)
- Albert Einstein College of Medicine (US)
- Hackensack University Medical Center (US)
- Feinstein Institute for Medical Research (US)
- Mayo Clinic (US)
- University of New Mexico Hospital (US)
- University of Wisconsin–Madison (US)
- Johns Hopkins University (US)
- University of Kansas (US)
- Medical University of South Carolina (US)
- University of California, San Francisco (US)
- Georgetown University (US)
- Washington University in St. Louis (US)
- Cornell University (US)
- University of Utah (US)
- Brown University (US)
- Hospital for Sick Children (CA)
- MedStar Georgetown University Hospital (US)
- Yale University (US)
- University of California San Diego (US)
- Massachusetts General Hospital (US)
- Madison Group (United States) (US)
- University of California, Irvine Medical Center (US)
- Hospital del Salvador (CL)
- Central Texas Veterans Health Care System (US)
- Philadelphia VA Medical Center (US)
- Centro Médico ABC (MX)
- Boston Children's Museum (US)
- Hanover College (US)
- New York University (US)
- Columbia University (US)
- University of Pennsylvania (US)
- The University of Texas Southwestern Medical Center (US)
- Vanderbilt University Medical Center (US)
- University of Cincinnati Medical Center (US)
- Philadelphia University (US)
Publication Details
- Journal
- Arthritis Care & Research
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1002/acr.25690
- Citations
- 6
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 10.01