Sex-specific Effects of Acute Stress on Emergence from Isoflurane Anesthesia via Brainstem Circuitry in Mice
This study identifies the LC NE → DRN GABA circuit and α1-adrenergic receptors in DRN GABA neurons as critical mediators in acute stress-induced emergence acceleration from isoflurane anesthesia in male mice.
Authors
- Xinghe Wang (ORCID: https://orcid.org/0000-0002-3178-0367)
- Kunwei Wu (ORCID: https://orcid.org/0000-0003-4074-0567)
- Shenglan Gong (ORCID: https://orcid.org/0000-0002-1427-5262)
- Jun‐Li Cao (ORCID: https://orcid.org/0000-0002-8932-4743)
- Su Liu (ORCID: https://orcid.org/0000-0002-8347-5399)
- Xin Meng
- Xiuli Zhao (ORCID: https://orcid.org/0000-0002-2998-3747)
- Zhi Yu (ORCID: https://orcid.org/0009-0006-7504-3680)
- Can Tang (ORCID: https://orcid.org/0009-0003-8905-3650)
Institutions
- Xuzhou Medical College (CN)
Publication Details
- Journal
- Anesthesiology
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1097/aln.0000000000005826
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00