Combined effect of nutritional inflammation as well as depression on mortality in middle-aged and elderly people with osteoporosis and osteopenia

A significant negative correlation exists between ALI and mortality risk in osteoporosis patients, while PHQ-9 scores correlate positively. Favorable nutrition and inflammation, coupled with the absence of depression, help reduce mortality risks.

Authors

Zhe Yang (ORCID: https://orcid.org/0000-0002-1925-2801)
Yazhou Liu (ORCID: https://orcid.org/0000-0003-2048-0729)
Yihong Li (ORCID: https://orcid.org/0000-0002-5476-1943)
Xiaodong Yang (ORCID: https://orcid.org/0009-0005-2528-4710)

Institutions

Dalian Medical University (CN)
Suzhou University of Science and Technology (CN)
Suzhou Vocational University (CN)
Suzhou Research Institute (CN)
Pudong Medical Center (CN)
China Medical University (CN)

Publication Details

Journal: PLoS ONE
Published: 2025-11-03
DOI: https://doi.org/10.1371/journal.pone.0335272
Primary Topic: Cardiac Health and Mental Health
Type: article
Field-Weighted Citation Impact: 0.00

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article

Combined effect of nutritional inflammation as well as depression on mortality in middle-aged and elderly people with osteoporosis and osteopenia

Zhe Yang, Yazhou Liu, Yihong Li, Xiaodong Yang

Nov 3, 2025

PLoS ONE

Cardiac Health and Mental Health

article

Combined effect of nutritional inflammation as well as depression on mortality in middle-aged and elderly people with osteoporosis and osteopenia

Zhe Yang, Yazhou Liu, Yihong Li, Xiaodong Yang

November 3, 2025article en

Abstract

A significant negative correlation exists between ALI and mortality risk in osteoporosis patients, while PHQ-9 scores correlate positively. Favorable nutrition and inflammation, coupled with the absence of depression, help reduce mortality risks.

PLoS ONEVol. 20(11)

Dalian Medical University (CN), Suzhou University of Science and Technology (CN), Suzhou Vocational University (CN), Suzhou Research Institute (CN), Pudong Medical Center (CN), China Medical University (CN)

Openalex Percentile: Top 50%

Cardiac Health and Mental Health

DOI Open Access PDF OpenAlex

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Combined effect of nutritional inflammation as well as depression on mortality in middle-aged and elderly people with osteoporosis and osteopenia — Zhe Yang, Yazhou Liu, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS