Personalized management and decision-making for non-ST-segment elevation acute coronary syndrome in vulnerable populations
Optimal management of elderly patients with NSTE-ACS requires a personalized approach. Antithrombotic therapy should be individualized, avoiding rigid guidelines. Less potent antiplatelet agents (e.g. clopidogrel) combined with direct oral anticoagulants (DOACs) offer improved safety in patients with AF. Early invasive strategies can reduce adverse events but may carry procedural risks in frail individuals. Systematic comprehensive geriatric assessment (CGA) should guide decision-making; and multidisciplinary care is essential to improving outcomes. Home-based or hybrid CR programs still need to be widely implemented and the integration of caregivers into them can enhance outcomes.
Authors
- César Jiménez-Méndez (ORCID: https://orcid.org/0000-0003-0282-3302)
- Fernando Rivero (ORCID: https://orcid.org/0000-0002-3676-0277)
- Fernándo Alfonso (ORCID: https://orcid.org/0000-0002-7480-2511)
- Albert Ariza‐Solé (ORCID: https://orcid.org/0000-0002-0819-6656)
- Pablo Díez‐Villanueva (ORCID: https://orcid.org/0000-0002-7661-651X)
- Pedro Cepas‐Guillén (ORCID: https://orcid.org/0000-0001-8814-7039)
- Héctor García‐Pardo
- Juan Sanchís (ORCID: https://orcid.org/0000-0002-6382-3376)
- Lidia Vilches
Institutions
- Bellvitge University Hospital (ES)
- Hospital Clínico Universitario de Valencia (ES)
- Centro de Investigación Biomédica en Red (ES)
- Hospital Clínic de Barcelona (ES)
- Hospital Universitario Puerta del Mar (ES)
- Hospital Universitario Río Hortega (ES)
- INCLIVA Health Research Institute (ES)
- Universidad Autónoma de Madrid (ES)
Publication Details
- Journal
- Expert Review of Cardiovascular Therapy
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1080/14779072.2025.2583939
- Primary Topic
- Acute Myocardial Infarction Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00