Anatomical, physiological and inflammatory characterization of nonculprit vessels in patients undergoing primary PCI for ST-elevation myocardial infarction in the presence of multivessel disease: Rationale and design of the PICNIC study
PICNIC will characterize the anatomical, physiological, and inflammatory features of NIRA lesions in STEMI patients treated with culprit-only PCI in order to develop an AI-based risk prediction model. If such a model is successful it could be used to inform personalized revascularization strategies.
Authors
- Rasha Al‐Lamee (ORCID: https://orcid.org/0000-0003-3752-5532)
- Charalambos Antoniades (ORCID: https://orcid.org/0000-0002-6983-5423)
- Richard J. Jabbour (ORCID: https://orcid.org/0000-0002-9028-2413)
- Nick Curzen (ORCID: https://orcid.org/0000-0001-9651-7829)
- Michael Mahmoudi (ORCID: https://orcid.org/0000-0003-1293-8461)
- Campbell Rogers (ORCID: https://orcid.org/0000-0003-3955-7650)
- Bon-Kwon Koo
- Mamas A. Mamas (ORCID: https://orcid.org/0000-0001-9241-8890)
- James Shambrook (ORCID: https://orcid.org/0000-0002-3084-5106)
- Tom Browne (ORCID: https://orcid.org/0000-0002-0825-6233)
- Jonathan Hinton (ORCID: https://orcid.org/0000-0003-1670-5550)
- Jonathon Leipsic (ORCID: https://orcid.org/0009-0002-3892-9029)
- Ausami Abbas
- Evangelos Kontopantelis
- Zoe Nicholas (ORCID: https://orcid.org/0000-0003-4674-3259)
Institutions
- University of British Columbia (CA)
- University Hospitals of Morecambe Bay NHS Foundation Trust (GB)
- Manchester Academic Health Science Centre (GB)
- St. Paul's Hospital (CA)
- John Radcliffe Hospital (GB)
- Seoul National University Hospital (KR)
- University Hospital Southampton NHS Foundation Trust (GB)
- University of Manchester (GB)
- Lung Institute (US)
- HeartFlow (United States) (US)
- St. Paul's Hospital (CA)
- University Hospitals Dorset NHS Foundation Trust
- Imperial College London (GB)
- Keele University (GB)
Publication Details
- Journal
- American Heart Journal
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1016/j.ahj.2025.107298
- Citations
- 1
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.01