Abnormal Blood Biomarkers and Cumulative Disability Burden in Middle-Aged and Older Adults: Evidence from Two Nationally Representative Surveys in the United States and China

The presence of abnormal levels in any two or all three of the systems significantly accelerated the rate of disability accumulation over a 4-year period. These findings highlight the importance of integrated biomarker monitoring for early identification of individuals at risk and inform the development of targeted preventive strategies.

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Publication Details

Journal
Journal of Cardiovascular Development and Disease
Published
2025-10-31
DOI
https://doi.org/10.3390/jcdd12110429
Primary Topic
Frailty in Older Adults
Type
article
Field-Weighted Citation Impact
0.00

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article

Abnormal Blood Biomarkers and Cumulative Disability Burden in Middle-Aged and Older Adults: Evidence from Two Nationally Representative Surveys in the United States and China

Alexander Wolthon, Raoping Tu, Hui‐Xin Wang, Yueping Li et al.
Journal of Cardiovascular Development and Disease
Frailty in Older Adults
article

Abnormal Blood Biomarkers and Cumulative Disability Burden in Middle-Aged and Older Adults: Evidence from Two Nationally Representative Surveys in the United States and China

Alexander Wolthon, Raoping Tu, Hui‐Xin Wang, Yueping Li, Jin-Jing Pei
article en

Abstract

The presence of abnormal levels in any two or all three of the systems significantly accelerated the rate of disability accumulation over a 4-year period. These findings highlight the importance of integrated biomarker monitoring for early identification of individuals at risk and inform the development of targeted preventive strategies.

Journal of Cardiovascular Development and DiseaseVol. 12(11)
Fujian Medical University (CN), Stockholm University (SE), Karolinska Institutet (SE)
Karolinska Institutet
Openalex Percentile: Top 61%
Frailty in Older Adults
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Abnormal Blood Biomarkers and Cumulative Disability Burden in Middle-Aged and Older Adults: Evidence from Two Nationally Representative Surveys in the United States and China — Alexander Wolthon, Raoping Tu, et al. · Journal of Cardiovascular Development and Disease (2025) | TGRS Research Map | TGRS