Synergistic DBNDD1–GDF15 Signaling Activates the NF-κB Pathway to Promote Colorectal Cancer Progression
This study highlights the crucial role of the DBNDD1-GDF15-NF-κB signaling pathway in colorectal cancer development, positioning DBNDD1 as a promising target for precision medicine strategies aimed at enhancing patient outcomes.
Authors
- Xiaomin Qi (ORCID: https://orcid.org/0009-0003-1493-5982)
- Caijuan Bai (ORCID: https://orcid.org/0009-0007-1905-1384)
- Chongge You (ORCID: https://orcid.org/0000-0002-3671-596X)
- Chaojun Wei (ORCID: https://orcid.org/0000-0002-1769-7655)
- Yonghong Li (ORCID: https://orcid.org/0000-0002-5198-3786)
- Dong Li (ORCID: https://orcid.org/0009-0004-5769-6501)
- Mengyuan Zhao (ORCID: https://orcid.org/0000-0002-5716-7931)
- Anqi Wang (ORCID: https://orcid.org/0000-0002-9798-985X)
Institutions
- Gansu Provincial Hospital (CN)
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Molecular Cancer Research
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1158/1541-7786.mcr-25-0153
- Citations
- 1
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.67