Molecular Characterization of Polyomavirus-Positive and Negative Merkel Cell Carcinoma
MCC oncogenesis and treatment response transcend viral status. While mutational analysis confirms previous findings, assessment of the transcriptome and tumor microenvironment suggests alternate therapeutic targets.
Authors
- Theresa W. Guo (ORCID: https://orcid.org/0000-0002-1689-3275)
- Isaac Brownell (ORCID: https://orcid.org/0000-0002-0090-9914)
- Soo J. Park (ORCID: https://orcid.org/0000-0002-5414-6772)
- Sharon Wu (ORCID: https://orcid.org/0000-0002-8336-6301)
- Curtis J. Perry (ORCID: https://orcid.org/0000-0003-3715-5332)
- Ling Gao (ORCID: https://orcid.org/0000-0001-7320-1442)
- Emil Lou (ORCID: https://orcid.org/0000-0002-1607-1386)
- Sourat Darabi (ORCID: https://orcid.org/0000-0002-3395-894X)
- Farah Abdulla (ORCID: https://orcid.org/0000-0002-3455-7566)
- Poorva Vaidya (ORCID: https://orcid.org/0000-0002-5506-4250)
- Varsha Prakash
- D. Bryant (ORCID: https://orcid.org/0009-0006-4751-5927)
Institutions
- Hoag Memorial Hospital Presbyterian (US)
- Oregon Health & Science University (US)
- UC San Diego Health System (US)
- Yale Cancer Center (US)
- Yale University (US)
- University of California San Diego (US)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (US)
- University of California, Irvine Medical Center (US)
- University of Minnesota Medical Center (US)
- UC Irvine Health (US)
- Caris Life Sciences (United States) (US)
Publication Details
- Journal
- Cancers
- Published
- 2025-10-31
- DOI
- https://doi.org/10.3390/cancers17213508
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00