Delay of Systemic Therapy Confers a Survival Benefit in Patients with Stage IV Non-Small-Cell Lung Cancer

UICC IV NSCLC patients with a delayed systemic therapy had a better overall survival than those with an early therapy. This observation supports a (qualified) waiting time for systemic therapies. Therapy timing may also be a relevant confounder in clinical studies.

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Publication Details

Journal
Cancers
Published
2025-10-31
DOI
https://doi.org/10.3390/cancers17213531
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Delay of Systemic Therapy Confers a Survival Benefit in Patients with Stage IV Non-Small-Cell Lung Cancer

Jörg Bäsecke, Nils Goeken, Joachim Hübner, Tobias Raphael Overbeck et al.
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Lung Cancer Treatments and Mutations
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Delay of Systemic Therapy Confers a Survival Benefit in Patients with Stage IV Non-Small-Cell Lung Cancer

Jörg Bäsecke, Nils Goeken, Joachim Hübner, Tobias Raphael Overbeck, Frank Griesinger, Rike Geiken-Weinstock, Michael Metz, Ralf G. Meyer, Peter Staib
article en

Abstract

UICC IV NSCLC patients with a delayed systemic therapy had a better overall survival than those with an early therapy. This observation supports a (qualified) waiting time for systemic therapies. Therapy timing may also be a relevant confounder in clinical studies.

CancersVol. 17(21)
Carl von Ossietzky Universität Oldenburg (DE), Klinikum Oldenburg (DE), Universitätsmedizin Göttingen (DE), Sankt-Antonius-Hospital Eschweiler (DE), Institute of Clinical Cancer Research (DE), Pius Hospital Oldenburg (DE), Hannover Clinical Trial Center (Germany) (DE), St.-Johannes-Hospital Dortmund (DE), Oncology Specialists (US), Intelligent Transport Systems Niedersachsen (DE)
Openalex Percentile: Top 54%
Lung Cancer Treatments and Mutations
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