The Systemic Link Between Oral Health and Cardiovascular Disease: Contemporary Evidence, Mechanisms, and Risk Factor Implications
Current findings highlight a significant oral-systemic connection through inflammatory and endothelial mechanisms. Strengthening interdisciplinary collaboration between dental and cardiovascular care providers is essential to translate this evidence into preventive and therapeutic practice. Further longitudinal and mechanistic studies are required to confirm causality and guide clinical integration.
Authors
- Raoul Vasile Lupușoru (ORCID: https://orcid.org/0000-0003-2653-4919)
- Ionuț Luchian (ORCID: https://orcid.org/0000-0003-0017-9672)
- Oana Butnaru (ORCID: https://orcid.org/0000-0002-7404-399X)
- Florinel Cosmin Bida (ORCID: https://orcid.org/0009-0001-0319-0538)
- Dana Gabriela Budală (ORCID: https://orcid.org/0000-0003-2312-6987)
- Teona Tudorici
- Mihaela Scurtu
- Gabriel Rotundu (ORCID: https://orcid.org/0009-0000-2536-7667)
- Florin Razvan Curca
- Dragos Ioan Virvescu (ORCID: https://orcid.org/0009-0005-6872-179X)
Institutions
- Grigore T. Popa University of Medicine and Pharmacy (RO)
Publication Details
- Journal
- Diseases
- Published
- 2025-10-31
- DOI
- https://doi.org/10.3390/diseases13110354
- Citations
- 4
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 5.86