Population Pharmacokinetics of a Novel Oral Fosfomycin Prophylactic Scheme in the Plasma and Prostate of Patients Undergoing Endoscopic Surgery for Benign Prostatic Hyperplasia
A prophylactic regimen of two doses of oral fosfomycin trometamol 3 g 12 h apart before undergoing prostatic surgery may grant effective concentrations in the prostatic tissue of patients for a 12 h vulnerable period.
Authors
- Eugenio Brunocilla
- Pierluigi Viale (ORCID: https://orcid.org/0000-0003-1264-0008)
- Valeria Rotaru
- Pier Giorgio Cojutti (ORCID: https://orcid.org/0000-0001-7135-4410)
- Federico Pea (ORCID: https://orcid.org/0000-0002-6966-7167)
- Pasquale Maria Berrino
- Lorenzo Bianchi (ORCID: https://orcid.org/0000-0001-7321-1536)
- Riccardo Schiavina (ORCID: https://orcid.org/0000-0003-4679-8196)
Institutions
- Azienda USL di Bologna (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Clinical Pharmacokinetics
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1007/s40262-025-01586-1
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00