Intracavitary infusion of FOLactis Lactobacillus leads to disappearance of MPE in patient with advanced lung adenocarcinoma

This case report presents the application of FOLactis, a lactic acid bacterium in situ vaccine, in the treatment of a lung adenocarcinoma patient who presented with malignant pleural effusion (MPE). An adult patient diagnosed with lung adenocarcinoma complicated by malignant pleural effusion (MPE) experienced favorable outcomes following the administration of intracavitary infusion of FOLactis, as conventional therapeutic approaches failed to yield satisfactory results. One month after the administration of FOLactis treatment, a subsequent CT examination revealed the complete resolution of malignant pleural effusion (MPE).

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Publication Details

Journal
Discover Oncology
Published
2025-11-03
DOI
https://doi.org/10.1007/s12672-025-03727-1
Primary Topic
Pleural and Pulmonary Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Intracavitary infusion of FOLactis Lactobacillus leads to disappearance of MPE in patient with advanced lung adenocarcinoma

Baorui Liu, Jie Shen, Sihui Zhu, Mingzhen Zhou et al.
Discover Oncology
Pleural and Pulmonary Diseases
article

Intracavitary infusion of FOLactis Lactobacillus leads to disappearance of MPE in patient with advanced lung adenocarcinoma

Baorui Liu, Jie Shen, Sihui Zhu, Mingzhen Zhou, Juan Zhang, Yan Zhao
article en

Abstract

This case report presents the application of FOLactis, a lactic acid bacterium in situ vaccine, in the treatment of a lung adenocarcinoma patient who presented with malignant pleural effusion (MPE). An adult patient diagnosed with lung adenocarcinoma complicated by malignant pleural effusion (MPE) experienced favorable outcomes following the administration of intracavitary infusion of FOLactis, as conventional therapeutic approaches failed to yield satisfactory results. One month after the administration of FOLactis treatment, a subsequent CT examination revealed the complete resolution of malignant pleural effusion (MPE).

Discover OncologyVol. 16(1)
Nanjing University of Chinese Medicine (CN), Nanjing Drum Tower Hospital (CN)
Government of Jiangsu Province, Nanjing University
Openalex Percentile: Top 54%
Pleural and Pulmonary Diseases
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