Intracavitary infusion of FOLactis Lactobacillus leads to disappearance of MPE in patient with advanced lung adenocarcinoma
This case report presents the application of FOLactis, a lactic acid bacterium in situ vaccine, in the treatment of a lung adenocarcinoma patient who presented with malignant pleural effusion (MPE). An adult patient diagnosed with lung adenocarcinoma complicated by malignant pleural effusion (MPE) experienced favorable outcomes following the administration of intracavitary infusion of FOLactis, as conventional therapeutic approaches failed to yield satisfactory results. One month after the administration of FOLactis treatment, a subsequent CT examination revealed the complete resolution of malignant pleural effusion (MPE).
Authors
- Baorui Liu (ORCID: https://orcid.org/0000-0002-2539-7732)
- Jie Shen (ORCID: https://orcid.org/0000-0003-3157-4640)
- Sihui Zhu
- Mingzhen Zhou
- Juan Zhang (ORCID: https://orcid.org/0009-0002-0374-5385)
- Yan Zhao (ORCID: https://orcid.org/0000-0003-0704-7410)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Drum Tower Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1007/s12672-025-03727-1
- Primary Topic
- Pleural and Pulmonary Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province
- Nanjing University