IgE elevation temporally associated with dermal Glufosinate ammonium exposure in an elderly patient: A case report from Vietnam

Glufosinate ammonium (GLA) is a nonselective herbicide of the phosphinic acid group, which is widely used in agriculture. Dermatologic toxicity has been rarely reported, especially in the elderly. We present the case of a 94-year-old female patient who developed irritant contact dermatitis and paresthesia after using her feet to stir 20 vials of Glufosinate ammonium herbicide in water. The patient presented with pruritus, numbness of the extremities, and a very high immunoglobulin E (IgE) elevation (855.5 IU/mL), which gradually decreased over time. This is the first report in Vietnam describing a delayed systemic IgE elevation due to dermal exposure to Glufosinate ammonium in a very elderly person.

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Publication Details

Journal
Asia Pacific Allergy
Published
2025-11-03
DOI
https://doi.org/10.5415/apallergy.0000000000000241
Primary Topic
Pesticide and Herbicide Environmental Studies
Type
article
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article

IgE elevation temporally associated with dermal Glufosinate ammonium exposure in an elderly patient: A case report from Vietnam

Dang Tuan Nguyen, Nguyễn Hữu Lâm
Asia Pacific Allergy
Pesticide and Herbicide Environmental Studies
article

IgE elevation temporally associated with dermal Glufosinate ammonium exposure in an elderly patient: A case report from Vietnam

Dang Tuan Nguyen, Nguyễn Hữu Lâm
article en

Abstract

Glufosinate ammonium (GLA) is a nonselective herbicide of the phosphinic acid group, which is widely used in agriculture. Dermatologic toxicity has been rarely reported, especially in the elderly. We present the case of a 94-year-old female patient who developed irritant contact dermatitis and paresthesia after using her feet to stir 20 vials of Glufosinate ammonium herbicide in water. The patient presented with pruritus, numbness of the extremities, and a very high immunoglobulin E (IgE) elevation (855.5 IU/mL), which gradually decreased over time. This is the first report in Vietnam describing a delayed systemic IgE elevation due to dermal exposure to Glufosinate ammonium in a very elderly person.

Asia Pacific Allergy
Hanoi Medical University (VN), Thai Nguyen University (VN), Bạch Mai Hospital (VN), Thai Nguyen University of Medicine and Pharmacy
Openalex Percentile: Top 74%
Pesticide and Herbicide Environmental Studies
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IgE elevation temporally associated with dermal Glufosinate ammonium exposure in an elderly patient: A case report from Vietnam — Dang Tuan Nguyen, Nguyễn Hữu Lâm · Asia Pacific Allergy (2025) | TGRS Research Map | TGRS