Impact of statins on metastatic castration-resistant prostate cancer patients receiving new hormonal agents

Our study suggests a prognostic impact of statin use in the PFS in patients receiving abiraterone or enzalutamide for mCRPC. This may be related to the enhancement of the antitumor activity of the ADT drugs, but also to the cardioprotective effects associated with statin use.

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Publication Details

Journal
Archivio Italiano di Urologia e Andrologia
Published
2025-11-03
DOI
https://doi.org/10.4081/aiua.2025.14179
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
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article

Impact of statins on metastatic castration-resistant prostate cancer patients receiving new hormonal agents

Roberto Jarimba, Ana Marta Ferreira, Arnaldo Figueiredo, Vasco Quaresma et al.
Archivio Italiano di Urologia e Andrologia
Cancer, Lipids, and Metabolism
article

Impact of statins on metastatic castration-resistant prostate cancer patients receiving new hormonal agents

Roberto Jarimba, Ana Marta Ferreira, Arnaldo Figueiredo, Vasco Quaresma, Tiago Sousa, Edgar Tavares-da-Silva, P. Nunes
article en

Abstract

Our study suggests a prognostic impact of statin use in the PFS in patients receiving abiraterone or enzalutamide for mCRPC. This may be related to the enhancement of the antitumor activity of the ADT drugs, but also to the cardioprotective effects associated with statin use.

Archivio Italiano di Urologia e AndrologiaVol. 97(4)
Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
Openalex Percentile: Top 61%
Cancer, Lipids, and Metabolism
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