Drug-drug interactions in anticoagulant therapy: a focus on oncology patients

Based on available data, we propose a practical approach to DDI assessment and clinical interpretation to support decision-making in patients with cancer requiring anticoagulation. This includes systematic screening for DDIs, tailoring anticoagulants during both initial and long-term treatment (primarily in the context of venous thromboembolism), providing patient counseling based on available evidence, and involving the pharmacy team in complex cases.