Test-retest reliability of non-invasive P2/P1 ratio and time to peak at rest and during isometric handgrip stress

The non-invasively measured P2/P1 ratio is a reliable metric in healthy young adults, maintaining its consistency even during significant cardiovascular stress. This study also establishes the MDC, providing a quantitative threshold to distinguish true physiological changes from measurement error. These findings support the use of the P2/P1 ratio for monitoring cerebrovascular dynamics and provide foundational data for future studies in clinical populations, such as critically ill patients.

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Publication Details

Journal
Medical Engineering & Physics
Published
2025-08-25
DOI
https://doi.org/10.1016/j.medengphy.2025.104421
Citations
1
Primary Topic
Heart Rate Variability and Autonomic Control
Type
article
Field-Weighted Citation Impact
1.39
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article

Test-retest reliability of non-invasive P2/P1 ratio and time to peak at rest and during isometric handgrip stress

Vítor Oliveira Carvalho, Rafael Pereira, Alinne Alves Oliveira, Filipe Lírio Malta et al.
1 citations
Medical Engineering & Physics
Heart Rate Variability and Autonomic Control
1.39
article

Test-retest reliability of non-invasive P2/P1 ratio and time to peak at rest and during isometric handgrip stress

Vítor Oliveira Carvalho, Rafael Pereira, Alinne Alves Oliveira, Filipe Lírio Malta, Mansueto Gomes-Neto, Gabriel Augusto Novaes
article en
1 citations

Abstract

The non-invasively measured P2/P1 ratio is a reliable metric in healthy young adults, maintaining its consistency even during significant cardiovascular stress. This study also establishes the MDC, providing a quantitative threshold to distinguish true physiological changes from measurement error. These findings support the use of the P2/P1 ratio for monitoring cerebrovascular dynamics and provide foundational data for future studies in clinical populations, such as critically ill patients.

Medical Engineering & PhysicsVol. 145(1)
Southwest Bahia State University (BR)
Openalex Percentile: Top 13%
Heart Rate Variability and Autonomic Control
1.39
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Test-retest reliability of non-invasive P2/P1 ratio and time to peak at rest and during isometric handgrip stress — Vítor Oliveira Carvalho, Rafael Pereira, et al. · Medical Engineering & Physics (2025) | TGRS Research Map | TGRS