The Protective Role of Haplotype -607A/-137C in the Promoter Region ofIL-18 Gene and HBV Infection Risk in the North Indian Population
The present study indicates that a double mutation (polymorphism) -607A/-137C in the IL-18 gene promoter region may contribute to the onset of HBV infection, while a single nucleotide polymorphism (-607C/-137C) may provide less susceptibility to HBV and may have a protective impact.
Authors
- Vandana Moudgil
- Jasbir Singh (ORCID: https://orcid.org/0000-0002-9531-6176)
- S. K. Sehrawat
Institutions
- Kurukshetra University (IN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-10-31
- DOI
- https://doi.org/10.2174/0113862073377295250911070504
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00