Abstract 4365627: Building Clinical Consensus on the Management of Cardiovascular Disease Risk in Obesity: An Initiative of the National Heart Foundation of Australia

Background: Obesity has become a critical health challenge, now affecting over a billion people globally. In Australia, approximately two-thirds of adults are living with overweight or obesity. Obesity significantly contributes to impaired quality of life and reduced life expectancy—two-thirds of which is attributable to cardiovascular disease (CVD). Despite its causal association with multiple cardiovascular conditions, obesity remains under-recognised and undertreated in cardiovascular care. Objective: To develop a clinical consensus statement that provides evidence-informed, practical guidance for health professionals on the management of overweight and obesity in the context of cardiovascular health. Approach: This initiative brought together clinical leaders and peak bodies from across Australia. A National Taskforce was established with representation from: cardiology, endocrinology, surgery, general practice, pharmacy, nutrition, exercise physiology, First Nations health, nephrology, public health and lived patient experience. The consensus was developed based on a comprehensive evidence review, broad stakeholder engagement and a National Stakeholder Forum which supported the prioritisation of issues within this clinical area. Results: Clinical consensus was established on the characterisation of obesity, including its recognition as a chronic disease, and its cardiovascular consequences within the syndrome of conditions known as cardiovascular-kidney-metabolic disease. Consensus recommendations were developed for non-pharmacological interventions, current and emerging pharmacological treatments, and surgical procedures. A particular focus was placed on new and emerging medicines and their impact on cardiovascular risk factors and clinical outcomes. Special consideration was given to high-priority groups, including First Nations peoples and culturally and linguistically diverse communities. Conclusion: This consensus statement drew together broad clinical expertise and sector consultation as well as the latest published evidence. It represents a fast and practical way of synthesising evidence in the rapidly evolving area of CVD management in obesity. It will support more consistent and effective management and guide equitable, evidence-based care. This initiative represents a critical step toward integrating obesity more fully into CVD prevention and management frameworks, both in Australia and globally.